巨幼细胞性贫血临床分析

The Clinical Analysis of Megaloblastic Anemia

目的探讨巨幼细胞性贫血的病因、临床特点及治疗效果。方法对72例巨幼细胞性贫血患者的发病原因、临床特征及疗效进行回顾分析。结果72例中40例(55.56%)有消化道症状,36例(50.00%)三系血细胞均减少,11例(15.28%)有神经症状,巨幼细胞性贫血需与全血细胞减少的疾病和消化道疾病及神经精神疾病进行鉴别。结论提高巨幼细胞性贫血相关知识的宣传教育,注意高发人群的饮食结构,加强营养,积极治疗原发疾病,应该是防治巨幼细胞性贫血的有效措施;注重消化系统疾病的防治及膳食结构调整、维生素B12和(或)叶酸治疗,绝大部分患者治疗效果显著。

Objective To discuss of the megaloblastic anemia etiology,clinical features and therapeutic effect. Methods 72 cases of megaloblastic anemia in patients with pathogenesis,elinical features and efficacy were analyzed retrospectively. Results Among 72 cases in 40 cases（55.56%）had gastrointestinal symptoms, 36 patients（50.00%）, three-line blood cells were decreased in 11 cases（ 15.28%）had neurological symptoms,megaloblastic anemia and pancytopenia need to diseases and digestive diseases and neuropsychiatric disease identification. Conclusion improve megaloblastic anemia associated knowledge,publicity and education,a^ention to high-fat diet groups,strengthening nutrition,active treatment of primary disease,prevention and treatment should be the megaloblastic anemia and effective measures, focusing on prevention and treatment of digestive diseases and food restructuring, Vitamin B12,and （or） folic acid treatment,most patients with the treatment effect is remarkable.