“蓝”类植物中的前体物质转化为“靛”的机制探讨

Study on mechanism of precursors transforming into indigo and indirubin in blue-genera plants

目的:通过查阅国内古籍和国外近代文献,介绍了"蓝"类植物的炮制品青黛从染料产业过渡到医药产业的过程;明确了生成靛的前体物质分别为靛红烷A、靛红烷B、靛红烷C和吲哚苷;阐明了前体物质转化为靛的机制;总结了多种测定前体物质含量的方法;为我国青黛炮制原理研究提供事实依据,为制靛工艺进入现代工业范畴奠定了基础。

Looking up into references at home and abroad ,we introduce the process of Indigo naturalis transforming from dyestuff industry into pharmaceutical industry.It is affirmed that the precursors of indigo and indirubin are isatan A、isatan B、isatan C and indicant.Meanwhile ,we clarify the mechanism of transformation for these precursors into indigo and indirubin.And we summarized methods of determination of these precursors.In summary,these references provide us accordance of study on processing principle of Indigo naturalis,and lay the foundation for technics of making indigo and indirubin entering into modern industry.