摘要
目的:评价米非司酮治疗子宫内膜异位症及子宫腺肌症的效果及安全性。方法:用米非司酮25mg,每日1次,口服,连续3个月,治疗16例子宫内膜异位症及腺肌症病人,观察临床症状的变化,治疗前后进行B超及血性激素检查。结果:所有病人痛经及盆腔痛症状消失,血性激素显示孕酮(P4)下降,促黄体素(LH)升高,未出现明显副作用。结论:米非司酮治疗子宫内膜异位症能明显改善病人症状,是安全有效的。
Objective: To evaluate the safety and effect of mifepristone (Ru486) on patients with endometriosis. Methods: Sixteen consecutive patients with pelvic endqmetriosis and adenomyosis were given Ru486 25 mg/d for 3 months. Clinical symptoms were observed, blood sexal hormene analysed and B-mode sonography examined before and after the treatment. Result: All the patients became amenorrhea and their dysmenorrhea and pelivic pain were relieved during the treatment. The sexal hormone measurment showed LH increased and P decreased. No significant side effect was obserred. Conclusion: Administration of Ru486 in patients with endometrlosis can safely and effectively relieve the symptoms
出处
《广西医科大学学报》
CAS
1998年第4期20-21,共2页
Journal of Guangxi Medical University