潘南金在术中补镁作用的临床观察

CLINICAL OBSERVATIONS ON THE EFFECT OF TREATING HYPOMAGNESEMIA WITH PANANGIN DURING OPERATIONS

目的：为了解麻醉、手术对血镁的影响及潘南金治疗后血镁浓度的变化。方法：40例病人随机分为两组，Ⅰ组用潘南金20～40ml术中、术后治疗；Ⅱ组为对照组未进行治疗。分别于麻醉前、麻醉手术后、术后第1天抽血测定血镁的变化；并于术中观察心电图的改变。结果：用潘南金治疗后，血镁维持在正常范围，且无心电图的改变；Ⅱ组血镁明显下降，与麻醉前及Ⅰ组比较均有统计学意义（P＜0．01），且有心电图的改变。结论；因麻醉、手术的原因引起血镁下降不容忽视，应注意镁离子的补充，潘南金是一种有效的补镁药物。

Objective: To observe the change of serum magnesemia during operation and anesthesia and treatment of hypomagnesemia with Panangin. Methods: 40 adult patients, ASA grade Ⅰ to Ⅱ, were divided at random into two groups. One group received treatment with 20 to 40 ml of Panangin. The other group was not treated with Panangin as a control. The serum magnesemia levels of the forty patients were measured before anesthesia, after operation and the frist day postoperatively. The change of EKG is also observed during surger.Result: In Ⅱ group the serum magnesemia decreased sigficantly (P <0. 01 ) after operation and EKG showed abnormal change. In Ⅰ group, after being treated with Panangin, the serum magnesemia returned to basic levels of preanesthsia. Conclusion: Hypomagnesemia can be effectively treated with Panangin