庚型肝炎病毒在肝炎及肝癌患者中感染情况

Infection of GBV-C Virus Among Hepatitis and HCC Patients

为研究庚型肝炎病毒在乙型肝炎、丙型肝炎、非甲—戊型肝炎及原发肝癌患者中的感染情况 ,选择临床肝炎患者血清及肝癌手术病人的术前血清、肝癌组织及癌旁组织。采用HGV RT PCR法检测标本中HGVRNA。结果 ,在临床乙型肝炎、丙型肝炎、非甲—戊型肝炎及肝癌手术病人中庚型肝炎感染率分别为 9% ( 12 / 130 )、10 % ( 3/ 30 )、17% ( 4 / 2 4 )、0 % ( 0 / 2 4 )。证明庚型肝炎是普遍存在的一种肝炎病毒 ,并与乙型肝炎、丙型肝炎有较高的重叠感染率 ,而与肝癌的相关性不大。

To study the infection status of GBV-C virus among HBV,HCV,nonA-E and HCC patients, serum of clinical hepatitis patients and HCC patients before operation, and the composition in/beside HCC were collected to examine HGV RNA of the samples, using HGV RT-PCR method. Results showed that among the clinical patients with HBV,HCV, nonA-E and HCC, HGV infection rates were 9%(12/130),10%(3/30),17%(4/24),0%(0/24) respectively, suggesting that HGV is a hepatitis virus with pervasive existence and has high superimposition infection rate with HBV and HCV but with little connection with HCC.