42.3 GHz毫米波电场治疗大鼠脊髓损伤的实验研究

Treatment of spinal cord injury with electric field of 42.3 GHz millimeter wave in rats

目的：研究毫米波对损伤脊髓修复的生物效应。方法：采用频率４２．３ＧＨｚ，波长７．１ｍｍ，输出功率密度２ｍＷ／ｃｍ２，７ｍＷ／ｃｍ２，２０ｍＷ／ｃｍ２的毫米波治疗大鼠损伤脊髓，３０ｍｉｎ，２次／ｄ×２０，观察组织学及皮层体感诱发电位（ＣＳＥＰ）、运动诱发电位（ＭＥＰ）变化。结果：７．１ｍｍ－７ｍＷ／ｃｍ２组、７．１ｍｍ－２０ｍＷ／ｃｍ２组与损伤组比较脊髓组织病变轻，ＣＳＥＰ潜伏期缩短。

Objective: To investigate the therapeutic effects of the electric field of millimeter wave on injured spinal cord. Methods: After the injured spinal cord was treated with the millimeter field in various parameters (7.1 mm 2 m W/cm 2, 7.1 mm 7 m W/cm 2 and 7.1 mm 20 m W/cm 2), the changes of histology, CSEP and MEP were observed. Results: The pathological changes were slighter and CSEP latency shorter in 7.1 mm 7 m W/cm 2 and 7.1 mm 20 m W/cm 2 groups than in the injured group. Conclusion: Millimeter wave in certain parameters can promote the reconstruction of the injured spinal cord.