摘要
本文以ＣＢ－ＨＲＰ逆行追踪和原癌基因ｃ－ｆｏｓ表达技术相结合，观察胃肠道伤害性刺激后中缝背核触液神经元Ｆｏｓ的表达。在中缝背核发现三种标记神经元，包括ＣＢ－ＨＲＰ逆行标记神经元（３０８）、Ｆｏｓ阳性神经元（４２）和ＣＢ－ＨＲＰ／Ｆｏｓ双重标记神经元（５）。本研究提示中缝背核含有一些具有双重功能的神经元，它们既在脑－脑脊液神经体液回路中传递信息。
By a doubling labelled method combining the retrograde tracing of CB HRP and the immunocytochemical technique Fos protein, the expression of Fos protein in the cerebrospinal fluid contacting neurons (csf cn) of dorsal raphe nucleus(DR)was observed following gastro intestinal noxious stimulation .There were three kinds of cells: CB HRP retrograde labelled cells(308) , Fos like cells(42).CB HRP/Fos double labelled cells(5) in the dorsal raphe nucleus following gastrointestinal noxious stimulation. The results suggested that there were some csf cn in DR which played a role not only in the message transmission between brain and csf but also in the functional modulation following gastrointestinal noxious stimulation.
出处
《中国应用生理学杂志》
CAS
CSCD
1998年第4期312-315,共4页
Chinese Journal of Applied Physiology
基金
江苏省自然科学基金
关键词
中缝背核
触液神经元
胃肠道伤害性刺激
FOS
dorsal raphe nucleus
cerebrospinal fluid contacting neurons
gastrointestinal noxious stimulation
Fos
