51例低浓度二硫化碳中毒神经传导速度与皮肤交感反射监测分析

目的探讨低浓度CS2中毒对51例患者的神经传导速度与皮肤交感反射的影响。方法选51例长期低浓度CS2接触者,并诊断为职业性慢性轻度CS2中毒且无中枢神经系统、心血管系统疾病及糖尿病,无其他中毒史者,采用丹迪Keypint型肌电图诱发电位仪进行NCV与SSR检测。结果NCV检测结果:运动神经潜伏期(DML)的阳性率与感觉神经传导速度(SNCV)的阳性率有显著差异(P<0.025)。DML检测:CS2的接触史小于等于10年与大于10年者之间阳性率的差异有统计学意义(P<0.05)。SNCV检测:CS2的接触史小于等于10年与大于10年者之间阳性率的差异有统计学意义(P<0.025)。SSR检测结果CS2的接触史小于等于10年DML的检测阳性率与SSR的检测阳性率之间有统计学意义(P<0.005)。CS2的接触史小于等于10年SNCV的检测结果与SSR的检测结果之间有统计学意义(P<0.005)。结论低浓度的CS2中毒者的周围神经损害,运动神经远端的DML的损要比SNCV损害的范围广,即运动神经要比感觉神经更易受损。并且随着接触史的延长运动神经、感觉神经、自主神经损害均加重。而接触史小于等于10年者中自主神经的损害要重于运动神经和感觉神经的损害。

Objective To discuss the effect of low density CS intoxication on the neurotic conduction velocity and Skin Sympathetic Response.Methods Select 50 chronic contacts of low density CS and diagnosis them with professional chronic mild CS intoxication and with no central nervous system,cardiovascular disease and diabetes.People with no other intoxication adopt Keypint type electromyogram evoked potentials equipment to inspect NCV and SSR.Results NCV testing result：motor neurone latent period＇s positive rate varies greatly from SNCV＇s positive rate.DML test：contacting period of CS is shorter or equal to 10 years compared with those who are longer than ten years,the difference of their positive rates are of great statistical difference（P0.05）.SNCV test：contacting period of CS is shorter or equal to 10 years compared with those who are longer than ten years,the difference of their positive rates are of great statistical difference（P0.025）.The SNCV testing result of CS contact whose period is shorter or equal to 10 years is of statistical signifi cance compared with those result of SSR.Conclusion Peripheral nerve of low density CS intoxicated people are damaged.The DML damage of motor neuro＇s tip is much wider than the damage of SNCV,ie.Motor neuro is more fragile than sensory nerve.With the stretching of contacting perid,the damage to motor neuron,sensory nerve,autonomic nerve are severed.However,among contacts whose period is shorter or equal to 10 years,the damage autonomic nerve is more severe to the motor neuron and sensory nerve.