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中国31省市门诊冠心病患者胆固醇控制现况 被引量:1

Control status of cholesterol among outpatients with heart artery disease in China
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摘要 目的:了解中国多省市门诊冠心病患者危险因素—胆固醇的控制情况。方法:2006年在中国31个省市自治区选择32家三级医院和32家二级医院。每家医院以研究启动时点起连续收集50例既往曾确诊冠心病的门诊患者,采用访谈形式,填写统一问卷,分析患者目前的胆固醇控制情况。以血脂资料完整的1806例门诊冠心病患者为研究对象。结果:(1)在1806例门诊冠心病患者中,男性占70.5%(1274例),女性占29.5%(532例),平均年龄(65±10)岁。(2)胆固醇达标率为26.2%,男性(30.5%)高于女性(15.8%,P<0.01),男性患者年龄越大胆固醇达标率越高(趋势性检验,P<0.01)。(3)按地理位置分为7个地区(华北、华东、华南、华中、东北、西北和西南),其中华中地区患者胆固醇达标率最高(39.7%),东北地区(14.9%),各地区间的差异具有显著统计学意义(P<0.01)。(4)不同医院级别的门诊冠心病患者胆固醇达标率存在差异,三级医院(30.0%)高于二级医院(22.6%,P<0.01)。结论:门诊冠心病患者的胆固醇达标率仅为26.2%,且在性别、年龄、医院级别和地区间存在差异,这在冠心病二级预防中应当引起重视。 Objective:To evaluate the current control status of cholesterol among outpatients with heart artery disease in China.Methods:Sixty-four hospitals across China,including 32 secondary hospitals and 32 tertiary hospitals were selected for baseline survey.Fifty outpatients diagnosed heart artery disease were recruited consecutively in each participated hospital.Information for 1806 patients was collected,and control status of cholesterol among the patients was analyzed.Results:(1)Mean age of the patients was 65 10.Seventy point five percent of the patients were male and 29.5% were female.(2)Overall 26.2% attained the cholesterol goal in the 1806 patients of heart artery disease,the goal attainment rate of cholesterol among male(30.5%) patients was higher than that among female(15.8%) patients.(3)The goal attainment rate of cholesterol was highest in middle China (39.7%)and lowest in northeast area(14.9%)among 7 geographic district(north China,east China,south China,middle China,northeast,northwest,southwest)(P〈0.01).(4) The goal attainment rate of cholesterol in tertiary hospitals(30.0%)was higher than that in secondary hospitals(22.6%,P〈0.01).Conclusions:Only 26.2% heart artery disease patients attained the cholesterol goal,the rate varied significantly among sex,different areas and different degree hospitals.It was essential to pay more attention on control of cholesterol for secondary prevention of cardiovascular disease.
出处 《中国冶金工业医学杂志》 2010年第2期131-133,共3页 Chinese Medical Journal of Metallurgical industry
关键词 冠心病 胆固醇 达标率 Heart artery disease Cholesterol Goal attainment rate
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  • 1Lupattelli G, De Vuono S, Mannarino E. Patterns of cholesterol metabolism: pathophysiological and therapeutic implications for dyslipidemias and the metabolic syndrome [J]. Nutr Metab Cardiovase Dis, 2011,21 (9) :620-627.
  • 2Bierklund M, Holm J, Onning G. Serum lipids and postprandial glucose and insulin levels in hyperlipidemic subjects after consumption of an oat beta-glucan-containing ready meal [J]. Ann Nutr Metab, 2008,52(2) :83-90.
  • 3Ellegard L, Andersson H. Oat bran rapidly increases bile acid excretion and bile acid synthesis: an ileostomy study [J]. Eur J Clin Nutr, 2007,61 (8) :938-945.
  • 4Reeves PG, Nielsen FH, Fahey GC Jr. AIN-93 purified diets for laboratory rodents: final report of the American institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet [J]. J Nutr, 1993,123 ( 11 ) : 1939-1951.
  • 5Rondanelli M, Opizzi A, Monteferrario F, et al. Beta-glucan-or rice bran-enriched foods: a comparative crossover clinical trial on lipidic pattern in mildly hypercholesterolemic men [J]. Eur J Clin Nutr, 2011,65(7) :864-871.
  • 6Lifschitz CH, Grusak MA, Butte NF. Carbohydrate digestion in humans from a beta-glucan-enriched barley is reduced [ J]. J Nutr, 2002,132 (9) :2593-2596.
  • 7Makelainen H, Anttila H, Sihvonen J, et al. The effect of beta- glucan on the glycemic and insulin index [J]. Eur J Clin Nutr, 2007,61 (6) :779-785.
  • 8Bartley GE, Yokoyama W, Young SA, et al. Hypocholesterolemic effects of hydroxypropyl methylcellulose are mediated by altered gene expression in hepatic bile and cholesterol pathways of male hamsters [J]. J Nutr, 2010,140(7) :1255-1260.
  • 9Russell DW. The enzymes, regulation, and genetics of bile acid synthesis [ J]. Annu Rev Biochem, 2003,72 : 137-174.
  • 10Costet P, Cariou B, Lambert G, et al. Hepatic PCSK9 expression is regulated by nutritional status via insulin and sterol regulatory element-binding protein le [J]. J Biol Chem, 2006, 281 (10): 6211-6218.

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