马钢高级职称1200例空腹血糖异常分布状况及其相关危险因素分析

Prevalence of elevated fasting glucose and related risk factors in 1200 Magang senior engineers

目的:调查马鞍山钢铁公司(马钢)高级职称人员空腹血糖(FPG)异常分布状况及其相关危险因素。方法:对1200例马钢高级职称人员检测肝肾功能、FPG、血脂、空腹胰岛素(FINS)、血压等,采用横断面调查研究方法分析FPG异常分布情况,Spearman相关分析及多元回归法评估其相关危险因素。结果:本组糖尿病检出率为6.6%,按2003年ADA标准FPG异常检出率为40.2%;随FPG水平增加,血压、血尿酸(UA)和肌苷(Cr)、血清总胆固醇(TC)水平及胰岛素抵抗指数(HOMA-IR)等显著升高;多元逐步回归分析显示,FPG与HOMA-IR、FINS、年龄、Cr及收缩压(SBP)独立相关。结论:马钢在职高级职称人员为糖尿病高危人群,早期对其空腹血糖异常(IFG)进行干预有可能减少其他代谢综合征组分聚集的几率,从而减少该群体心血管事件的发生。

Objective：To investigate the prevalence of elevated fasting glucose in senior engineers in service of Magang and to explore risk factors of elevated fasting glucose related.Methods：To calculate the prevalence of elevated fasting glucose by analysis physical examination data in 2006,and evaluate the risk factors for elevated fasting glucose by stepwise multiple regression.Results：The prevalence of diabetes mellitus was 6.6%,The prevalence of impaired fasting glucose based on 2003 ADA criteria was 40.2%.With fasting glucose elevating,blood pressure,serum uric,serum creatinine,total cholesterol et al were significant increased.The independent risk predictors for fasting glucose level were HOMA-IR,fasting insulin levels,age,serum creatinine and systolic blood pressure by multiple stepwise regression.Conclusions：Magang senior engineers were higher risk population for diabetes mellitus.The lower fasting glucose levels,the fewer the accumulation of components of metabolic syndrome.