摘要
目的 探讨热应激创伤对PC12细胞热休克蛋白70(HSP70)的影响。方法用免疫细胞化学方法检测热应激对PC12细胞HSP70表达水平的变化。结果在热损伤过程中HSP70和细胞增殖能力均显菩高于对照组。结论HSP70高水平表达作为是神经细胞自我保护的机制之一。
Objective: To investigate the changes of heat shock protein 70 (HSP70) expression levels in neurons in traumic stress. Methods: The expression amounts of HSP70 were determined of PC12 cells using immunocytochemical approach during heat stress. Results: The expression levels of HSP70 increased in heat stress. In the present study, the proliferations of PC 12 cells also increased. Conclusions. High level expressions of HSP70 is one of protective mechanisms in PC 12 cells.