102例妊娠合并血小板减少的妊娠结局分析

Pregnancy outcome analysis of 102 cases gestational thrombocytopenia

目的探讨妊娠合并血小板减少对母婴的影响。方法回顾性分析中山大学附属第三医院2004年1月至2008年12月妊娠合并血小板减少102例孕妇的临床资料,35例血小板计数<50×109/L为I组,67例血小板计数50×109/L～100×109/L为II组,对两组妊娠结局进行分析。结果I组剖宫产率、早产、产后出血、新生儿窒息的发生率均高于II组(P<0.05)。结论妊娠合并重度血小板减少对母婴有较大危害,在积极治疗原发病的同时,应酌情予以肾上腺皮质激素、丙种球蛋白及输血小板等治疗;血小板计数50×109/L～100×109/L孕妇:如果没有出血倾向,孕期无需特殊处理,但需要定期检测血小板计数。

Objective To investigate the impact of gestational thrombocytopenia on the outcome of mother and infant. Methods Analysed retrospectively 102 cases including 35 cases of I group（50 ×10^9/L platelets counts） and 67 cases of II group（50 ×10^9/L-100×10^9/L platelets counts ） from January 2004 to Decepmber 2008,compared the outcome of pregnancy between two groups.Results The incidence of the rate of cesarean section、premature delivery,postpartum hemorrhage 、neonatal asphyxia were markedly higher in I group than those of II group （ P〈0.05）.Conclusion Severe gestational thrombocytopenia does great harm to mother and infant,we should timely treat primary dieases and assisted corticosteroid 、immunoglobulin and platelets transfusions.No intervention is necessary during pregnancy unless there is clinical bleeding symptoms,but should regular examine in 50 ×10^9 /L-100 ×10^9 /L platelets counts patients.