国产罗哌卡因用于颈丛神经阻滞的临床观察

Use of domestic-made ropivacaine in cervical plexus nerve block

目的比较康博宁、耐乐品及布比卡因分别用于颈丛神经阻滞的临床效果。方法选择60例择期手术的甲状腺囊肿患者，术前随机分为3组，行颈丛神经阻滞。Ⅰ组：0．25％布比卡因；Ⅱ组：0．25％耐乐品；Ⅲ组：0．25％康博宁。观察患者麻醉起效时间、感觉阻滞情况、术中镇痛效果，记录声嘶、呼吸困难等并发症发生率。疼痛评定采用视觉模拟评分（VSA）法，0—2为效果优，3～5为效果良，6～7为效果差，8～10为无效。结果三组VAS评分、麻醉起效时间无明显差异（P〉0．05），三组镇痛效果无明显差异（P〉0．05），三组麻醉并发症发生率无显著性差异（P〉0．05）。结论康博宁和耐乐品用于颈丛神经阻滞与布比卡因无显著差异，可在临床颈丛神经阻滞中推广应用。

Objective To compare the clinical effect of Kangboning and Naropin or bupivacaine uses in block anesthesia of cervical plexus. Methods Choose 60 patients of parathyroid cyst to selective operation, divided into three groups randomly, use block anesthesia of cervical plexus. Group Ⅰ ：0. 25% bupivacaine; Group Ⅱ 0. 25% Naropin; Group Ⅲ： 0. 25% Comparison. Observes the patient of the time come into effect, and the analgesia effect ; record the percentage of hoarseness, dyspnea etc. Results The three group of VAS and the time come into effect were not significant （ P 〉 0. 05 ）, Three groups of the analgesia effects were not significant （ P 〉 0. 05 ）. Three groups of the complications were not significant （ P 〉 0. 05 ）. Conclusion 0. 25 % Kangboning or Naropin use in block anesthesia of cervical plexus provides a satisfactory effect.