摘要
目的:通过近红外激光热疗对人宫颈癌Caski细胞的体内体外实验研究,评估该项技术的可行性。方法:首先对人宫颈癌Caski细胞进行近红外激光照射;再对裸鼠肿瘤模型进行近红外激光诱导照射。通过针对宫颈癌细胞的体内体外试验,观察肿瘤细胞的形态变化,肿瘤模型的病理变化以及肿瘤体积质量的变化等,从而分析该疗法的可行性和效果。结果:体内体外实验表明,宫颈癌Caski细胞及裸鼠成瘤模型经近红外激光热疗作用后,细胞明显变形、坏死,细胞增殖受到明显抑制,其中4w功率组的细胞抑制率达77.04%。裸鼠种植的肿瘤出现明显坏死,其质量体积明显减小。结论:近红外激光热疗可以明显抑制人宫颈癌Caski细胞的增值,可使宫颈癌肿瘤模型体积减小,可作为宫颈癌治疗的一种有效方法。
Objective：To study the therapeutic effect of near-infrared laser hyperthermia on human Caski cells of cervical carcinoma in vitro and in vivo.Methods：By in vitro and in vivo experiments,the morphologic changes of cells and the pathological changes of tumour models were observed.We can estimate the effect of the treatment.Results：Near-infrared laser could significantly inhibit the proliferation of Caski cells,.Animal – experiment showed that it could significantly inhibit the weight and volume of cervical carcinoma.Conclusions：Near-infrared laser could inhibit the proliferation of human Caski cells and the weight and volume of cervical carcinoma.It could open up a new treatment of cervical carcinoma.
出处
《航空航天医药》
2010年第3期298-300,共3页
Aerospace Medicine
