期刊文献+

常规体外授精短时授精后6h行卵胞浆内单精子注射治疗受精失败34例 被引量:12

下载PDF
导出
摘要 目的:探讨短时授精后6h后早期实施卵胞浆内单精子注射(ICSI)治疗受精失败的临床价值。方法:对34例常规体外授精(IVF)短时受精后6h未出现第二极体的卵子实施早期补救ICSI。结果:34例患者共获353枚MⅡ卵子,受精后6h观察,均未出现第二极体立即实施ICSI,296枚正常受精,受精率为83.9%,4枚卵子出现3个原核,优质胚胎率56.4%,妊娠率41.2%。结论:通过常规IVF短时授精后6h早期观察第二极体是否排出确定受精情况并对未排出第二极体的卵子及时实施补救ICSI,可成为治疗受精失败的有效方法。
作者 马学工
出处 《实用医学杂志》 CAS 北大核心 2010年第6期986-987,共2页 The Journal of Practical Medicine
  • 相关文献

参考文献5

  • 1Kuczynski W,Dhont M,Grygoruk C,et al.Rescue ICSI of unfertileized oocytes after IVF[J].Hum Reprod,2002,17 (9):2423-2427.
  • 2Pellestor F,Andreo B,Areal F,et al.Maternal aging and chromosom al abnormalities:New data drawn fromin vitrounfertilized human oocytes[J].Hum Genet,2003,112(2):195-203.
  • 3马学工,党小红,纪冰.常规IVF完全失败后行补救ICSI10例[J].实用妇产科杂志,2007,23(8):501-502. 被引量:7
  • 4Nagy Z P,Liu J,Joris H,et al.Time course of oocyte activation,pronucleus formation and cleavage in human oocytes fertilized by intracytoplasmic sperm injection[J].Hum Reprod,1994,9 (9):1743-1748.
  • 5Chen C,Kattera S.Rescue ICSI ofoocytes that failed to extrude the second polar body 6 h post-insemination in conventional IVF[J].Hum Reprod,2003,18(10):2118-2121.

二级参考文献5

共引文献6

同被引文献86

  • 1杨麦贵,杨阳,郝晓柯,张竹映,郑善銮,樊爱琳,程晓东,周铁成,池巍.男性不育者精液中一氧化氮和顶体酶、透明质酸酶、酸性磷酸酶的变化[J].检验医学,2005,20(5):431-433. 被引量:7
  • 2张丽红,王克华,李娟,江平,张梅心,董云玲,胥玉梅,刘锦云,张琦,王洪岩.缩短受精前卵母细胞培养和精卵共孵育时间对妊娠结局的影响[J].生殖医学杂志,2006,15(2):127-129. 被引量:17
  • 3李晓虹,于丛一,麦美琪,李予,苏宁,魏春霞,陈静华,杨冬梓,张清学.常规IVF不受精周期行补救卵母细胞单精子注射[J].中山大学学报(医学科学版),2007,28(2):188-191. 被引量:28
  • 4邢琼,曹云霞,魏兆莲,周平,章志国,赵济华.IVF与ICSI周期实验室及临床结果观察[J].安徽医科大学学报,2007,42(3):320-322. 被引量:10
  • 5Francavilla S,Cordeschi G,Pelliccione F,et al.Isolated teratozoospermia: a cause of male sterility in the era of ICSI-2007.Frontiers in Bioscience 12:69-88.
  • 6Rybouchkin AV,Vander Straeten F ,OuatackerJ, et al.Fertilization and pregnancy after assisted oocyte acti vation and intracytoplasmic sperm injection in case of round-headed sperm associated with deficient oocyte activation capacity.1997,Fertil Steril, 68:1144-1147.
  • 7Liu DY, Baker HW G. Human sperm bound to the zone pellucida have normal nuclear chromatin assessed by A cridine orange flurescence []].Hum Ikeprod.2007,22:1597-1602.
  • 8Henkel P,.,Franken DR,Habenicht UF. Zone pellucida as physiological trigger for the induction of acrosome reaction. Andrologia,1998,30:275-280.
  • 9Miyara F, Aubriot FX ,Glissant A, et al. Multiparameter analysis of human oocytes at metaphase Ⅱ stage after IVF failure in non-male infertility. HumReprod,2003,18 ( 70 ): 1494-1503.
  • 10Dirnfled M,Bider D,Korfman M, et al. Shortened exposure of oocytes to spermatozoa improve in-vitro fertilization outcome: a prospective randomized ,controlled study[J]. Hum Reprod, 1999,14(10):2562-2564.

引证文献12

二级引证文献45

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部