人多肽链延伸因子1α四个反转录假基因的鉴别与定位

Identification and Localization of 4 Retropseudogenes of the Human Polypeptide Chain Elongation Factor-1α

人多肽链延伸因子１α基因ＥＥＦ１Ａ是一个在蛋白质合成过程中起重要作用的看家基因。通过对已有ＧｅｎＢａｎｋ、ＧＤＢ等数据库的综合分析，鉴定了４个人类多肽链延伸因子１α基因的反转录假基因，并分别将其精细定位于４ｑ２５、７ｐ１５－２１、９ｑ３４和１９ｑ１３上。

The gene for human polypeptide chain elongation factor-1α(EEF1A) is a house-keeping gene which plays an important role in the process of protein synthesis By means of comprehensive analysis in the database of Genbank, GDB and ect, we identify 4 retropseudogenes of EEF1A and finely localized to 4q25, 7p15-21, 9q34 and 19q13, respectively