突触小泡膜表面突起与微管联系的超微结构研究

THE ULTRASTRUCTURAL STUDY ON THE MEMBRANE SURFACE PROCESS OF THE SYNAPTIC VESICLE ASSOCIATES WITH THE MICROTUBULE

本研究用透射电镜技术观察了大脑皮质（视区）和海马（CA1区和CA3区）的神经终末内的突触小泡和微管间的联系。结果揭示：在适当的超薄切片样品上，常显示出突触小泡膜表面上有短的突起，说明突触小泡是借其膜表面的短突与其它小泡和微管进行联系的。除小泡外，在微管的表面也见一些短突并与小泡发生接触。本文首次报道了用透射电镜方法观察脑内小泡-微管借表面短突连接的联系，提示突触小泡膜表面和微管表面的短突在轴浆运输机制中负有重要的作用。

In order to understand the association between the synaptic vesicle and microtubule in the nerve endings, the present work examined rat cerebral cortex (visual area) and hippocampus (CA1 and CA3 regions) by transmission electron microscopy.The results showed that short processes on the membrane surface of the synaptic vesicle were often revealed on the apposite ultrasections. It was indicated that the synaptic vesicle were connected with other vesicles and microtubules by the short process of vesicle membrane surface. Besides the vesicle, a few short processes were also encountered on the surface of the microtubulesand contacted with the vesicles. This article reported the vesicle-microtubule association by the surface process observed for the first time by using transmission electron microscopy. It was suggested that the short processes of the synaptic vesicle and microtubule play a important role for axoplasm transport.