ECT检查230例肺癌患者脊柱骨转移的临床分析

Clinical characteristics of vertebral metastasis in 230 cases of lung cancer under emission computed tomography

目的探讨肺癌脊柱骨转移的基本临床特点。方法以全身骨静态扫描(ECT)检查有阳性发现的肺癌脊柱骨转移病例230例为研究对象,所有肺癌病例均有明确的病理学诊断,所有脊柱骨转移病例均有功能影像和结构影像学证据的支持,采用回顾性统计方法,对病人基本临床资料进行分析,用卡方检验的方法比较组间差异,p<0.05为有统计学差异。结果230例肺癌脊柱骨转移病例中,能确定病理类型与细胞分化程度者,腺癌118例(60.20%),低分化癌107例(72.79%)。在有明确肺癌发病部位记录的212例病例中,右肺119例(56.13%);左肺上叶在全肺5个部位之中例数最多,为59例(27.83%)。单部位脊柱骨转移有125例(58.96%),多部位脊柱骨转移有105例(49.53%);单部位脊柱骨转移中以胸椎占多数,有65例,占总病例数的28.26%。结论本组病例发生脊柱骨转移的原发癌发生部位所占比例最高者为左肺上叶;病理类型所占比例最高者为腺癌,且低分化癌所占比例最高,单部位脊柱骨转移中以胸椎占多数。

Objective To explore the fundamental clinical characteristics of vertebral metastasis in lung cancer cases. Methods 230 patients of vertebral metastasis in lung cancer were collected according to emission computed tomograpy （ECT） and pathological diagnosis with well-defined imaging changes. Retrospective studies were carried out to analysis a set of fundamental clinical data of those cases. Results 118 in 230 cases were adenocarcinoma （60. 20%）, and 107 of them were cases located on superior lobe of left lung which surpass other 4 physical regions. Single-spot vertebra metastasis is comparable to multi-spot vertebra metastasis as the proportions are 54. 35% and 45.65%, respectively. Conclusion Adenocarcinoma types are most frequent and most of adenocarcinomas are poorly differentiated. Primary focuses in superior lobe of left lung are prone to facilitating metastasis and thoracic vertebrae are most vulnerable in the cases of single-spot