多巴胺与硫酸镁联用治疗支气管哮喘60例的临床疗效分析

Analysis of effects of dopamine,magnesium sulfate and aminophylline on treatment of severe bronchial asthma

目的观察多巴胺、硫酸镁联用治疗重症支气管哮喘中的疗效及副作用。方法将114例重症支气管哮喘患者随机分为治疗组60例和对照组54例，两组均在补液、抗炎、解痉、平喘、吸氧等常规治疗的基础上，治疗组加用多巴胺10mg与硫酸链2．5g；对照组用氨茶碱0．25g，分别加入10％葡萄糖250ml静滴、速度10-20滴／min，1次／d，疗程3～7天。结果两组疗效无明显差异，但多巴胺与硫酸镁联用的副作用明显低于氨茶碱组（P〈0．05）。结论多巴胺与硫酸镁联用在治疗重症支气管哮喘中疗效显著，不良反应少，值得临床参考。

Objects To observe and compare the curative effects and side effects of the dopamine, magnesium sulfate and aminophylline on treatment of severe bronchial asthma. Methods The patients were divided into two groups, including the control group and the treatment group. Patients in the treatment group were treated with dopamine 10mg, magnesium 2.5g and 10% glucose 250ml, intravenously, whereas the patients in the control group were treated with aminophylline 0.25g and 10% glucose 250ml, intravenously. Results There was no obvious difference between the two groups in curative effects, but the side effects of the dopamine and magnesium were lower than that of the other group. Conclusion The curative effects of dopanmine and magnesium are effective and little adverse reaction.