摘要
目的分析结肠黑变病(MC)的临床特点。方法2004年1月-2008年12月结肠镜检查3256例患者中检出MC患者87例作为MC组,从非MC组中随机抽取100例作为对照组,对其临床资料进行回顾分析。结果MC检出率为2.7%,男女比例1.35∶1;MC组服用泻剂者(74.7%)多于对照组(22.0%),差异有统计学意义(P<0.05);MC组息肉发生率为56.3%高于对照组的20.0%,且MC组中服用蒽醌类泻剂者占绝大多数,差异均有统计学意义(P<0.05);MC组中炎性病变、腺瘤性息肉发现率明显高于对照组,差异有统计学意义(P<0.05)。结论MC好发于中、老年人,MC易合并结肠炎性病变及腺瘤性息肉,腺瘤性息肉属于癌前期病变,故对于MC患者进行定期结肠镜检查是非常必要的。
Objective To study the clinica character of melanosis coli（MC）.Methods From january 2004 to december 2008,3 256 cases detected in MC 87 cases as the MC group,MC group from a non-random sample of 100 cases as control group,the clinical data were analyzed retrospectively.Results MC detection rate was 2.7%,compared for men and women was1.35∶1;MC group taking laxatives（74.7%）was more than control group（22.0%）,the difference was statistically significant（P0.05）;MC group the incidence of polyps（56.3%）was higher than that in control group（20.0%）,and the MC group taking anthraquinone laxatives accounted for the vast majority（P0.05）;The inflammatory lesions and adenomatous polyp detection rate in MC group were significantly higher,the difference was statistically significant（P0.05）.Conclusion MC is predilection in middle-aged and aged people,MC easily combin colitis lesions and adenomatous polyps,adenomatous polyps is precancerous lesions.MC colonoscopy is necessary.
出处
《临床合理用药杂志》
2010年第5期19-20,共2页
Chinese Journal of Clinical Rational Drug Use
