摘要
介绍了目前处于研究开发中的Ⅲ类抗心律失常药以及它们所作用的离子通道;讨论了该类药物发展趋势,指出虽然开发Ⅲ类药物已成共识,但对开发何种类型的Ⅲ类药物作为抗心律失常药,人们还有不同的看法;
The class Ⅲ antiarrhythmic agents which are in development and the ion channels which seem to be affected by those agents were introduced in this review. The possible trend to develop potential class Ⅲ agents and the preliminary relationship between structure and antiarrhythmic activity of class Ⅲ agents were also discussed.
出处
《药学进展》
CAS
1998年第4期221-227,共7页
Progress in Pharmaceutical Sciences
关键词
抗心律失常药
离子通道
钾通道
Class Ⅲ antiarrhythmic agent Ion channels Potassium channel blocker