成都大学2008年新生乙肝病毒感染情况分析

Analysis on Infection of Hepatitis B among Freshman in Chengdu University in 2008

目的了解新生HBV感染状况,以加强对HBV的预防和控制,为今后的防治工作提供科学依据。方法对2008年入学的6 322名新生用酶联免疫法(EL ISA)检测病毒性乙型肝炎五项血清学标志及测定ALT(丙氨酸氨基转移酶)。结果HBsAg阳性率为6.52%,性别间差异有显著性(P<0.01),其血清学标志物阳性模式(单纯HBsAb阳性除外)有12种,以HBsAg+HBeAg+抗-HBc阳性;HBs Ag+抗-HBe+抗-HBc阳性;HBs Ag+抗-HBc三种模式多见,其构成比分别为26.82%,28.89%,13.67%。HBs Ag阳性者与阴性者ALT异常率分别为1.46%及0.36%,两者之间差异有显著性(P<0.01)。结论为预防和控制乙肝在高校的传染,在新生中应加强乙型肝炎感染的控制和预防工作。

Objective To investigates the situation of HBV infection in freshmen of universities.Methods Serum five indicators of the infection of hepatitis B were detected with Enzyme-linked immune assay（ELISA）,and ALT was detected in freshmen of university in 2008.Results The positive rate of HBsAg was 6.52% whit significant difference（P0.05） between male and female.HBV infection had twelve patterns.The main HBV infection patterns were as follows： HBsAg,HBeAg and anti-HBc positive（26.82%）.HBsAg,anti-HBe and anti-HBc positive（28.89%）.HBsAg,anti-HBc positive（13.67%）.The abnormal rate of ALT was 1.46% among the cases of positive HBsAg.The abnormal rate of ALT was 0.36% among the cases of negasitive HBsAg.There is an obvious difference between them on the he abnormal rate of ALT（P0.01）.Conclusion In order to prevent the infec-tion of hepatitis B in universities,we should to strengthen control and preventive measures for freshman.