瑞芬太尼与异氟醚对全身麻醉患者术后苏醒的效果

Analysis on the Effect of Remifentanil and Isoflurane for Postoperative Recovery from General Anesthesia

目的探讨全身麻醉手术后瑞芬太尼与异氟醚对患者苏醒时间及术后意识的影响。方法120例ASAⅠ-Ⅱ级的择期非心脏手术全身麻醉患者。随机分为试验组与对照组各60例。2组除麻醉维持[试验组:异丙酚1～2mg/(kg.min)与瑞芬太尼0.1～1.0μg/(kg.min)复合泵入,对照组:吸入1%～3%异氟醚]外,其他麻醉方法均相同。记录2组停药后呼之睁眼时间、拔管时间、语言应答时间等麻醉恢复指数及术后是否出现躁动现象。结果2组患者手术时间、麻醉时间无显著差异(P>0.05),试验组较对照组苏醒时间、拔管时间、语言应答时间均短,术后出现躁动情况轻(均P<0.05)。结论瑞芬太尼复合异丙酚在全身麻醉术后苏醒时间短,术后意识较平稳。

Objective To compare the influence of remifentanil combined and isoflurane on the postoperative recovery time and consciousness during general anesthesia.Methods One hundred and twenty ASA Ⅰ-Ⅱ patients scheduled for elective non-cardiac surgical operations were randomly divided into the experimental group （n=60） and control group （n=60）.In two groups the anesthetic method was the same except anesthetic maintenance [experimental group：0.1～ 1.0 μg/（kg·min） remifentanil and 1～2 mg/（kg·min） propofol;control group：1%～3% isoflurane].The time of opening eye,extubation and verbalization after operation were recorded.Results There was no significant difference in operative time and anesthetic time between two groups （ P 0.05）;the time of opening eye,extubation,and verbalization in the experimental group was shorter than that in the control group （P0.05）;the postoperative irritable condition in the experimental group was lower than that in the control group （P0.05）.Conclusion The anesthetic recovery time of patients is shorter after injecting remifentanil combined with propofol;the postoperative consciousness is stable.