期刊文献+

衰老性肌肉丢失与机械生长因子相关研究的进展 被引量:4

Research progress of relationships between sarcopenia and mechanic growth hactor
下载PDF
导出
摘要 衰老性肌肉丢失是由衰老引起肌肉质量下降和肌肉力量减弱。在机械刺激和组织损伤的情况下,机械生长因子MGF出现表达,具有增加肌肉质量的能力,另外还可能受到生长激素的影响。衰老进程中,骨骼肌MGF表达下降,激活有限的卫星细胞,不能完全修复受损细胞。而运动影响衰老骨骼肌MGF表达,进而减缓衰老性肌肉丢失的发生。 Sarcopenia is the degenerative loss of skeletal muscle mass and strength in aging.The expression of MGF is only detectable after mechanical stimulation and tissue damage,with the ability to increase muscle mass,and also affected by growth hormone.In aging process,the declined MGF expressions of aging skeletal muscle activate the limited satellite cells,and can not completely repair damaged cells.Exercise affects the MGF expression of aging skeletal muscle and reduces sarcopenia.The paper reviews the relationship between sarcopenia and MGF,and gives references for treatment.
出处 《武汉体育学院学报》 CSSCI 北大核心 2010年第4期70-74,共5页 Journal of Wuhan Sports University
基金 河北省自然基金(C2008000177) 河北师范大学研究生基金(200801017)
关键词 衰老性肌肉丢失 机械生长因子 卫星细胞 生长激素 运动 sracopenia MGF satellite cell growth hormone exercise
  • 相关文献

参考文献36

  • 1Morley J E,Baumqartner R N,Roubenoff R,et al.Sarcopenia[J].J Lab Clin Med,2001,137(4):231-243.
  • 2R·ckl KS,Hirshman MF,Brandauer J,et al.Skeletal muscle adaptation to exercise training:AMP-activated protein kinase mediates muscle fiber type shift[J].Diabetes,2007,56(8):2062-9.
  • 3Bonnefoy M.Sarcopenia,muscle function and prevention[J].Nut Clin Metab,2004,18:175-180.
  • 4Water D.L,Baumgartner R.N,Garry,P.J.Sarcopenia:current perspectives[J].The Journal of Nutrition,Health&Aging,2000,4(3):133-139.
  • 5Ryall JG,Schertzer JD,Lvnch GS.Cellular and molecular mechanisms underlying age-related skeletal muscle wasting and weakness[J].Biogerontology,2008,9(4):213-228.
  • 6Liu W,Thomas S G,Asa S L,et al.Myostatin is a skeletal muscle target of growth hormone anabolic action[J].J.Clin.Enocrinol,2003,88:5490-5496.
  • 7McNeil C J,Doherty T J,Stashuk DW,et al..Motor unit number estimates in the tibialis anterior muscle of young,old,and very old men[J].MuscleNerve,2005,31(4):461-467.
  • 8Doherty,Brown W F.The estimated numbers and relative size of thenar motor units as selected by multiple point stimulation in young and older adults[J].Muscle Nerve,1993,16:355-366.
  • 9Cooper R.N,Butler-Browne G.S,Mouly V.Human muscle stem cells[J].Curr.Opin.Pharmacol,2006,6 (3),295–300.
  • 10Gibson M.C,Schultz E.Age-related differences in absolute numbers of skeletal muscle satellite cells[J].Muscle Nerve,1983,6:574-580.

二级参考文献14

  • 1史仍飞,危小焰.机械生长因子(MGF)与运动[J].体育科学,2006,26(6):90-92. 被引量:10
  • 2Issurin VB. Vibrations and their applications in sport. J Sports Med Phys Fitness, 2005, 45(3): 324-336.
  • 3Luo J, McNamara B, Moran K. The use of vibration training to enhance muscle strength and power. Sports Med, 2005, 35(1):23-41.
  • 4Goldspink G. Cellular and molecular aspects of muscle growth, adaptation and ageing. Gerodontology, 1998, 15 (1): 35-43.
  • 5Oxlund BS, Qrtoft G, Andreassen TT, et al. Low-intensity, high-frequency vibration appears to prevent the decrease in strength of the femur and tibia associated with ovariectomy of adult rats. Bone, 2003, 32(1): 69-77.
  • 6Ron Maughan, Michael Gleeson. The biochemical basis of sports performance. OXFORD University Press, 2004.68-69.
  • 7Momken I, Lechene P, Koulmann N, et al. Impaired voluntary running capacity of creatine kinase-deficient mice. J Physiol, 2005, 565(Pt 3): 951-964.
  • 8Huijing PA, Jaspers RT. Adaptation of muscle size and myofascial force transmission: a review and some new experimental results. Scand J Med Sci Sports, 2005, 15(6): 349-380.
  • 9Campos GE, Luecke TJ, Wendeln HK, et al. Muscular adaptations in response to three different resistance-training regimens: specificity of repetition maximum training zones. Eur J Appl Physiol, 2002, 88(1-2):50-60.
  • 10Adams GR, Cheng DC, Haddad F, et al. Skeletal muscle hypertrophy in response to isometric, lengthening, and shortening training bouts of equivalent duration. J Appl Physiol, 2004, 96(5): 1613-1618.

共引文献11

同被引文献35

  • 1邓启烈,莫伟彬.骨骼肌卫星细胞在组织工程与运动损伤修复中的应用[J].中国老年学杂志,2014,34(10):2899-2901. 被引量:5
  • 2李卫国.牵张反射[J].生物学通报,1989,24(4):6-8. 被引量:1
  • 3史仍飞,危小焰.机械生长因子(MGF)与运动[J].体育科学,2006,26(6):90-92. 被引量:10
  • 4Thomell LE,Lindstrom M, Rennault V, et al. Satellite ceils and training in the elderly[J]. Scand J Med Scisports,2003,13:48-55.
  • 5Grounds MD, Garrett KL, Beilharz MW. The transcription of MyoD1 and myogenin genes in thymic cells in vivo[J]. Exp Cell Res,1992,198(2):357-361.
  • 6Wozniak AC, Kong J, Bock E, et al. Signaling satellite-cell activation in skeletal muscle: markers, models, stretch, and potential alternate pathways[J].Muscle Nerve,2005,31(3):283- 300.
  • 7Kadi F,Eriksson A, Holmner S, et al. Cellular adaptation of the trapezius muscle in strength-trained athletes[J]. Histochem Cell Bio1,1999,111(3):189-195.
  • 8Hikida RS, Walsh S, Barylski N,et al. Is hypertrophy limited in elderly muscle fibers? A comparison of elderly and young strength-trained men[J].Basic Appl Myo1,1998,8:419-427.
  • 9Petrella JK, Kim JS, Cross JM, et al.Efficacy of myonuclear addition may explain differential myofiber growth among resis- tance-trained young and older men and women[J].Am J Physi- ol Endocrinol Metab, 2006,291(5):E937-E946.
  • 10Barone R, Bellafiore M, Leonardi V, et al. Structural analysis of rat patellar tendon in response to resistance and endur- ance training[J]. Scand J Med Sci Sports, 2009,19(6):782- 789..

引证文献4

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部