中医辨证治疗强直性脊柱炎疗效观察

Curative Effect Observation on Ankylosing Spondylitis Treated by Traditional Medicine Dialectical

目的:观察中医辨证治疗强直性脊柱炎(AS)的疗效和安全性。方法:100例AS随机分为治疗组和对照组各50例,对照组给予依那西普皮下注射;治疗组在对照组基础上加用中医辨证口服中药治疗。两组疗程均为6个月。治疗前后分别检测晨僵时间、Schober试验、胸廓扩张度、指地距、枕壁距、BASDAI评分、BASMI评分、血沉、C反应蛋白。结果:治疗6个月后,治疗组总有效率显著高于对照组(P<0.05);治疗组临床疗效指标较治疗前显著改善(P<0.05或P<0.01)。口服中药未发现严重不良反应。结论:在西医治疗的基础上加用中医辨证论治,可显著提高疗效,病人耐受性好。

Objective：To observe the efficacy and safety of traditional Chinese medicine dialectical in treatment on patients with ankylosing spondylitis（AS）.Methods：100 cases of AS were randomly divided into treatment group（50 cases） and control group（50 cases）,The control group was treated with subcutaneous etanercept injections;The treatment group was treated with oral application of Traditional Chinese Medicine Application of TCM treatment on the basis of the control group.Course of two groups were 6 months.The following indicators were used to detect before and after treatment：time of morning stiffness,Schober test,thoracic expansion degrees,refers to land distance,pillow-wall distance,BASDAI score,BASMI score,ESR,C-reactive protein.Results：After 6 months,the treatment group was significantly higher than the control group in the total efficiency rate of the treatment（P 0.05）;Treatment group after treatment compared with pre-treatment significantly improved efficacy in clinical indicators（P 0.05 or P 0.01）,oral medicine found no serious adverse reactions.Conclusion：Application of Traditional Chinese Medicine Treatment of dialectic can significantly increase the efficacy of therapy based on Western medicine,the patient well tolerated.