吸烟对呼吸道感染患者的微生态影响

EFFECTS OF SMOKING ON MICROECOLOGY OF PATIENTS WITH YESPIRATORY INFECTION

呼吸道感染是常见病多发病，而呼吸道感染可导致微生态失调。有报道，宿主的任何病理变化都可作为生态失调的微观环境因素。微观环境对正常微生物群的影响是直接的；而且是主要的。为此，我们对吸烟和被动吸烟者的微生态变化及呼吸道感染患者微生态的变化以及二者之间的关系进行了研究。以进一步探讨吸烟对呼吸道感染患者直接或间接的影响。研究结果表明，吸烟及被动吸烟者患反复呼吸道感染的年发生率明显高于不吸烟者。健康对照组与患者口咽部菌群数相比有显著差异，无论是吸烟还是不吸烟的患者菌群含量均高于健康对照组（Ｐ＜００５）。结果表明，吸烟不仅有害于自身健康，而且危害被动吸烟者，其对呼吸道微生态的影响都是一致的，即可导致微生态失调。

Respiratory infection is a common and frequent disease,and it may cause microecological imbalance.It was reported that any pathological changes in host might serve as microenvironmental factor for ecological imbalance.The influence of microenvironment on normal microbial population is direct and important.Therefore the microecological changes in smokers and passive-smokers and the patients with respiratory infection and the relationship between them were studies in order to approach the direct or indirect effects of smoking on the pationts with respiratory infection.The results showed that annual incidences of recurrent respiratory infection were higher in smokers and passive smokers than that in non-smokers.The amounts of oral flora were significantly greater in smoking or non-smoking patients than that in health control(p<0 05). It was indicated that smoking not only injured the health of selves,smoking may induce microecological imbalance,thus causing repiratory disease.