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布托啡诺静脉注射对肌间沟入路臂丛神经阻滞效果的影响 被引量:2

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摘要 目的探讨布托啡诺静脉注射对肌间沟入路臂丛神经阻滞效果的影响。方法选择40例ASAⅠ~Ⅱ级,并涉及前臂或手部尺、桡侧手术的成年患者。随机分为实验组(A组)和对照组(B组),每组20例。均采用3.75 g/L罗哌卡因+6.6 g/L利多卡因混合液进行肌间沟入路臂丛神经阻滞,注射容量0.45 mL/kg,局麻药注射后每5 min记录桡侧和尺侧VAS评分。局麻药注射后A组即静脉注射布托啡诺1 mg(5 mL),B组静脉注射生理盐水5 mL。持续记录尺、桡侧VAS评分降至0时间、镇痛持续时间、血流动力学变化以及不良反应等。结果40例患者有36例获得优良以上麻醉效果。两组获得的各时段VAS评分,桡侧皮区明显低于尺侧,P<0.05。布托啡诺给药后尺侧皮区VAS评分降至0时间A组为(19.90±4.52)min,明显短于B组的(25.05±4.10)min(P<0.05);镇痛持续时间A组(470.65±83.90)min,B组(364.70±95.06)min,差异有显著性(P<0.05)。两组均未发现明显血流动力学变化?不良反应或麻醉并发症。结论肌间沟入路臂丛神经阻滞并静脉使用布托啡诺,可加快尺侧皮区起效时间,延长神经阻滞持续时间,并可提高臂丛神经阻滞效果的质量。
出处 《广东医学》 CAS CSCD 北大核心 2010年第6期777-779,共3页 Guangdong Medical Journal
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参考文献11

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