微量热法表征邻香草醛氨基葡萄糖Schiff碱锌配合物的抗菌活性

MICROCALORIMETRIC CHARACTERIZATION OF THE ANTIBACTERIAL ACTIVITY BY o VANILLIN GLUCOSAMINE SCHIFF BASE ZINC COMPLEX

用微量热法测定了大肠杆菌（细菌）及其在Ｚｎ－ｏ－ＶＧ（ｏ－ＶＧ：邻香草醛氨基葡萄糖Ｓｃｈｉｆ碱）作用下不同温度下的热谱；计算了它的生长速率常数ｋ、传代时间Ｇ、抑制率Ｉ、总产热量Ｑ、单个细菌的平均产热Ｑ０和单位时间平均每个细菌的产热量Ｑ０；建立了细菌生长代谢各种参量之间的函数关系，探计了在不同温度和药物作用下细菌的生长代谢；发现可用ｔｇ、ｔｒ和ｔ表征细菌的生长代谢和药物的抗菌活性。

The power time curves of E.coli effected by Co(Ⅲ) 2,4 L at the different temperature have been determined by the LKB2277 Bioactivity Monitor. The multiplication rate constans k,G,I,Q,Q 0 and 0 were calculated and the relationship formulas have been set up. A lot of useful information was obtaied.