摘要
α－甲基烯丙基醇是合成一些大环内酯（ｍａｃｒｏｌｉｄｅ），聚醚抗生素（ｐｏｌｙｅｔｈｅｒａｎｔｉｂｉｏｔｉｃｓ）和信息素的重要中间体［１］。立体选择性地合成α－甲基烯丙基醇是当今最富挑战性的课题之一。正是因为这类化合物具有广泛的合成价值，以致于有三十...
α methylhomoallylic alcohols are important intermediates used for synthesizing some macrolides and polyether antibiotics.The reactions used for synthesizing α methylhomoallylic alcohols,in which the reactions of Crotomic Bromide with aldehydes take place in the presence of gallium,have advantages of being in high yield and high pregioselectivity.
出处
《化学研究与应用》
CAS
CSCD
1998年第6期643-649,共7页
Chemical Research and Application
关键词
一锅法
镓
甲基烯丙基醇
合成
巴豆基溴
醛
One pot,Regioselectivity,Gallium,α methylhomoallylic alcohols
