一种新型杯[4]芳烃的合成

Synthesis of a Novel Calix[4]arene

本文通过对特丁基杯［４］芳烃的酚羟式烷基化和苯环特丁基位上的ＩＰＳＯ－硝化制备了一系列对硝基［４］芳烃烷基醚，烷基分别是ｎ－Ｃ４Ｈ９（３ａ）、ｎ－Ｃ８Ｈ１７（３ｂ）、ｎ－Ｃ１２Ｈ２５（３ｃ）和ｎ－Ｃ１６Ｈ３３（３ｄ）。＾１ＨＮＭＲ表明所有新的杯［４］芳烃都具有锥形（ｃｏｎｅ）构象。

Four tetraalkylethers (2a - 2d, n - C4H9, n - CgH17,n - C12H25, n - C16H33)of p -tertbutylcalix[4]arene and the corresponding ethers of p - nitrocalix[4] arenes(3a - 3d)were prepared in the cone conformation by the etheration with NaH as abase in DMF and the ipso - nitration.1H NMR show that all new calix[4]arenes are cone conformation.