微生态制剂治疗老年习惯性便秘86例临床分析

Microbial treatment of senile habitual constipation Clinical analysis of 86 cases

目的观察微生态制剂美常安胶囊治疗老年习惯性便秘的临床疗效。方法采用随机、双盲、平行的方法对本院两年来门诊和住院老年习惯性便秘患者86例,给予美常安胶囊口服,一次2粒,3次/d,连续治疗4 w,并以同期80例给予安慰剂治疗作为对照组。观察两组治疗后患者的排便间隔时间、便质、排便费力情况及便秘的伴随症状等。结果治疗组总有效率79.1%,与对照组30.0%相比,差异有统计学意义(P<0.01)。治疗期间治疗组未出现不良反应,无死亡及其它严重不良反应发生。结论双歧杆菌四联活菌片对老年习惯性便秘疗效确切,安全可靠,副作用小。

Objective To observe the regular capsule probiotics America senile habitual constipation clinical efficacy. Methods A randomized, double-blind, parallel approach to the hospital two years, outpatient and hospitalized elderly patients with 86 cases of habitual constipation to give the United States often an oral capsule, a 2, 3 times / d, continuous treatment for 4 weeks, and in the same period 80 cases of as a control group given placebo. Were observed after treatment of patients with defecation interval, then quality, defecation trouble situation and the associated symptoms of constipation. Results The total effective rate 79.1%, 30.0%, compared with the control group, there was a significant difference （P〈0.01）. The treatment group during treatment without adverse reactions, no death and other serious adverse reactions. Conclusion viable Bifidobacterium quadruple tablet senile habitual constipation efficacy accurate, safe and reliable, side effects.