期刊文献+

胎儿终丝形态学及超微结构研究 被引量:9

Study on the morphology and ultrastructure of fetus ilium terminale
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摘要 目的观察正常人胎儿终丝形态及其超微结构,为研究脊髓栓系综合征患儿的终丝结构提供参照标准。方法切除并测量11具人新鲜流产胎儿终丝,取其纵、横切面行光镜和扫描电镜观察。结果终丝由1—5μm直径的弹簧样纵向胶原纤维束组成,纤维束呈层分布,每层之间及层内纤维束有空隙。层间隙、束间隙及束内每根纤维间由横向细网状纤维连结,胶原纤维束交叉连结各束间及层间纤维。高倍电镜可见横向纤维及纵向纤维最小单位直径约0.13μm。弹性纤维分散在胶原纤维束内或集中排列在胶原纤维束间。间隙可见少量毛细血管。结论终丝中远段由有序排列的弹簧样纤维结构和少量毛细血管组成的精细三维结构组成,终丝的结构及成分改变可能与脊髓栓系综合征的发病密切相关。 Objective The filum terminale (FT) plays an important role in the pathophysiology of tethered cord syndrome (TCS). The study on morphology and uhrastructure of fetus FT can provide reference standard for diagnosis of TCS . Method Eleven fresh human aborted fila fetuses had been measured and removed. Transversal and longitudinal sections of the middle, and distal thirds of FT were submitted to light microscopy analysis with four different techniques. Four fila were selected for longitudinal and transversal scanning electron microscopy analysis. Results The bulk of the FT was composed of 1 μm to 5 μm thick spring like longitudinal bundles of collagen separated by 5 μm to 30 μm layer intervals and 1 μm to 5 μm intervals in the layer, although a small quantity of capillaries and other elements may be present. A delicate (0. 13 μm) meshwork of collagen transversal fibers connects these bundles and fibers in every bundle. Collagen bundles could also be found between layers and bundles. Abundant longitudinally oriented elastic fibers were found inside or between collagen bundles. A complex tridimensional structure was evidenced on electron microscopy. Conclusions A complex tridimensional structure composed by ordered arrangement of spring like fibers and small quantity of capillaries should elicit considerable elastic properties to the FT. It's alternation of structure and element maybe involved closely in TCS.
出处 《中华神经外科杂志》 CSCD 北大核心 2010年第2期151-154,共4页 Chinese Journal of Neurosurgery
基金 河南省科技厅重点攻关项目(001170648)
关键词 终丝 胎儿 脊髓栓系综合征 解剖学 Filum terminale, fetus Tethered cord syndrome Anatomy
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  • 1李强,石志才.神经电生理技术在脊髓栓系综合征诊治中的应用[J].脊柱外科杂志,2003,1(5):298-302. 被引量:10
  • 2周国昌,徐建民,周天健,纪树荣,石晶.脊髓拴系综合征MRI图像与手术所见的关系[J].中国脊柱脊髓杂志,1994,4(4):145-148. 被引量:60
  • 3石志才,李家顺,贾连顺.脊髓栓系综合征的研究现状[J].中华外科杂志,1995,33(12):734-737. 被引量:44
  • 4司丕成,刘福云,夏冰.神经干细胞在终丝中分布研究[J].临床小儿外科杂志,2005,4(6):425-429. 被引量:5
  • 5Harmeier JW.The normal histology of the intradural filum terminale[J].Arch Neurol Psychiatry,1933,32:308-316.
  • 6Alexandr Chvatal,Miroslava Anderova,Richard K,et al.Membrane currents and morphological properties of neurons and glial cells in the spinal cord and filum terminale of the frog[J].Neuroscience Research,2001,40(1):23-35.
  • 7Miklos Rethelyi,Erika Lukacsi,Csaba Boros.The caudal end of the rat spinal cord:transformation to and ultrastructure of the filum terminale[J].Brain Research,2004,1028(2):133-139.
  • 8Choi BH,Kim RC,Suzuki M,et al.The ventriculus terminalis and filum terminale of the human spinal cord[J].Hum Pathol,1992,23(8):916-920.
  • 9Tubbs RS,Murphy RL,Kelly DR,et al.The filum terminale externum[J].J Neurosurg Spine,2005,3(2):149-152.
  • 10Yamada S,Zinke DE,Sanders D.Pathophysiology of "tethered cord syndrome"[J].Neurosurg,1981,54(4):494-503.

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  • 1鲍南,吴水华,杨波,顾硕,褚君,胡明,施诚仁.儿童终丝牵拉综合征60例诊治分析[J].临床小儿外科杂志,2010,9(4):248-251. 被引量:1
  • 2赵春植,金日华,李相龙.胸腰段椎管内巨大终丝室管膜瘤1例[J].延边大学医学学报,2007,30(2):132-132. 被引量:1
  • 3Tortori - Donati P, Rossi A, Cama A. Spinal dysraphism: A review of neuroradiological features with embryological correlations and proposal for a new classification [ J ]. Pediatr Neuroradiol, 2000,42 ( 7 ) : 471 - 491.
  • 4Fabiano A J, Khan MF, Rozzelle C J, et al. Preoperative predictors for improvement after surgical untethering in occult tight filum terminale syndrome[ J ]. Pediatr Neurosurg,2009,45 (4) :256 - 261.
  • 5Bao N, Chen ZH, Gu S, et al. Tight ilium terminale syndrome in children : Analysis based on positioning of the conus and absence or presence of lumbosacral lipoma [ J ]. Child Nerv Syst, 2007,23 (10) : 1129 - 1134.
  • 6Selcuki M, Vatansever S, Inan S,et al. Is a ilium terminale with a normal appearance really normal [ J ] ? Child Nerv Syst ,2003,19 ( 1 ) :3 - 10.
  • 7Hsu AR, Hou LC, Veeravagu A, et al. Resolution of syringomyelia after release of tethered cord [ J ]. Surg Neurol,2009,72 (6) :657 - 661.
  • 8Milhorat TH, Bolognese PA, Nishikawa M, et al. Association of Chiari malformation type I and tethered cord syndrome : Preliminary results of sectioning filum terminale[ J ]. Surg Neurol,2009,72 ( 1 ) :20 -35.
  • 9Cardoso M, Keating RF. Neurosurgical management of spinal dysra- phism and neurogenic scoliosis [ J ]. Spine, 2009,34 ( 17 ) : 1775 - 1782.
  • 10Iskandar BJ, Fulmer BB, Hadley MN,et al. Congenital tethered spinal cord syndrome in adults[J]. Neurosurg Focus,2001,10( 1 ) :e7.

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