2横田慎一 熊毅雄治 内海光朝.A Pharmacokinetic Study of MCI—186,a novel drug for cerebrovascular disease in elderly and young healthy subjects[J].临床药理,1997,28(3):693-702.
3lnamasu J, Suga S, Sato S, et al. Postischemic hypothermia attenuates apoptotic cell death in transient focal ischemia in rats. Acta Neurochir Suppl, 2000, 76:525 - 527.
4Takagi K, Ginsberg MD, Globus MY, et al. Effect of hyperthermia on glutamate release in ischemic penumbra after middle cerebral artery occlusion in rats. Am J Physiol, 1994, 267:H1770 - H1776.
5Reith J, Jorgensen HS, Pedersen PM, et al. Body temperature in acute stroke: relation to stroke severity, infarct size, mortality, and outcome.Lancet, 1996, 347:422-425.
6Diringer MN, Reaven NL, Funk SE, et al. Elevated body temperature independently contributes to increased length of stay in neurologic intensive care trait patieras. Crit Care Med, 2004, 32:1489 - 1495.
7Hajat C, Hajat S, Sharma P. Effects of poststroke pyrexia on stroke outcome : a meta-analysis of studies in patieras. Stroke, 2000, 31:410-414.
8Nolan JP, Morley PT, Vanden Hoek TL, et al. Terapeutic hypothermia after cardiac arrest: an advisory statement by the advanced life support task force of the International Liaison Committee on Resuscitation.Circulation, 2003, 108:118 - 121.
9Kammersgaard LP, Rasmussen BH, Jorgensen HS, et al. Feasibility and safety of inducing modest hypothermia in awake patieras with acute stroke through surface cooling: A case-control study: the Copenhagen Stroke Study. Stroke, 2000, 31:2251 - 2256.
10Schmutzharct E, Engelhardt K, Beer R, et al. Safety and efficacy of a novel intravascular cooling device to control body temperature in neurologic intensive care patients: a prospective pilot study. Crit Care Med, 2002, 30:2481-2488.
7Shichinohe H, Kuroda S, Yasuda H, et al. Neuroprotective effects of the free radical scavenger Edaravone (MC1-186) in mice permanent focal brain isehemia[J]. Brain Res, 2004,1029 (2) : 200-206.
8Shiehinohe H, Kuroda S, Yasuda H, et al. Neuroproteetive effects of the free radical scavenger Edaravone ( MCI - 186) in mice permanent focal brainlschemia[ J]. Brain Res ,2004,1029 (2) :200 - 206.
9Schaarschmidt H,Prange HW,Reiber H.Neuron-specific enolase concentrations in blood as a prognostic parameter in cerebrovascular diseases[J].Stroke,1994,25(3):558-565.
10Shimon A,Tstsuski K.Expression of Anti-apoptotic and neuroprotective effects of edaravone following transient focal ischemia in rats[J].Eur J Pharmacol,2005,516:125-130.
