老年人消化性溃疡并发出血的危险因素分析

Analysis of Risk Factors of Hemorrhage in the Elderly with Peptic Ulcer

目的探讨老年人消化性溃疡并发出血的相关危险因素,为其预防和治疗提供可靠依据。方法收集2005年5月～2009年5月入住我院60岁及以上的消化性溃疡患者的临床资料,按照本次住院期间是否并发出血,将其分为两组进行比较、分析,并对其中并发出血的相关因素进行多因素Logistic回归分析。结果 342例老年人消化性溃疡患者并发出血有119例(34.3%),比较两组患者一般情况、基础疾病、临床特征,对可能并发出血相关因素行多因素Logistic回归分析,结果显示女性、基础疾病、服用非甾体类消炎药(NSAIDs)、无腹痛和复合性溃疡有统计学意义(P<0.01)。结论女性、基础疾病、服用NSAIDs、无腹痛和复合性溃疡是老年人消化性溃疡并发出血的高危因素,其中复合性溃疡是其独立危险因素。

Objective To investigate the risk factors of hemorrhage in the elderly with peptic ulcer（ PU ） in order to provide a reliable basis for the prevention and treatment of bleeding. Methods The data of the patients with PU aged 60 years old in the Central People＇s Hospital of Huizhou from May 2005 to May 2009 were collected and analyzed, and they were divided into two groups based on whether they had bleeding. The risk factors of bleeding in the elderly with PU were analyzed by multivariate logistic regression. Results Of the 342 elderly PU,119 （34.3%）had bleeding. The comparative analysis was performed in general conditions,basic disease and clinical characteristics. Logistic regression analysis showed that female,basic disease,NSAIDs intake,no abdominal pain and compound ulcer were correlated with bleeding in the elderly with PU（ P〈0.01 ）. Conclusion The risk factors which are closely related to the occurrence of bleeding in the elderly with PU are female, basal disease, NSAIDs intake, no abdominal pain and compound ulcer,in which compound ulcer is an independent risk factor of bleeding in the elderly with PU.