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端粒、端粒酶和垂体腺瘤 被引量:1

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摘要 端粒酶(telomerase)属于逆转录酶家族,其过度表达与细胞的永生化和癌变直接相关,其结构和功能决定了它在肿瘤治疗等方面具有广泛的应用前景。垂体腺瘤为一种良性肿瘤,但其具有侵袭性的特性,端粒酶的表达与垂体腺瘤的侵袭性有一定的相关性。但是国际上关于二者的关系有两种截然不同的观点:一种认为端粒酶的表达与垂体瘤的侵袭性呈正相关,而另一种认为二者没有直接的相关性。因此,进一步研究端粒、端粒酶和垂体腺瘤等良性肿瘤的关系具有非常重要的意义。本文就端粒、端粒酶及其与垂体腺瘤之间的关系研究作一综述。
出处 《国际神经病学神经外科学杂志》 2010年第1期31-34,共4页 Journal of International Neurology and Neurosurgery
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同被引文献14

  • 1王忠诚.蝶鞍区肿瘤-垂体腺瘤,王忠诚神经外科学.第2版,北京:湖北科技出版社,2005,620-648.
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