沙丁胺醇联合丙酸倍氯米松治疗成人哮喘的疗效观察

Observation on Effect of Salbutamol Combined with Beclomethasone in Treating Adult with Suffocative Catarrh

目的:探讨沙丁胺醇加丙酸倍氯米松治疗成人哮喘的临床效果。方法:将2008年1月至2009年1月间在我院住院治疗的哮喘患者84例随机分为A组、B组和C组,A组单纯吸入沙丁胺醇,B组单纯吸入丙酸倍氯米松,C组联合应用二丙酸倍氯米松和沙丁胺醇气雾剂,评估三组治疗效果。结果:治疗后三组患者PEF均较治疗前好转,三组分别比较差异具有统计学意义(P<0.05)。A组、B组PEF明显低于C组,两组分别比较差异具有统计学意义(P<0.05);A组PEF与B组比较差异无统计学意义(P>0.05)。A组、B组无症状天数明显低于C组,两组分别比较差异具有统计学意义(P<0.05);A组无症状天数与B组比较差异无统计学意义(P>0.05)。A组总有效率为71.42%,B组为75.00%,C组为100.00%;A组、B组总有效率明显低于C组,两组分别比较差异具有统计学意义(P<0.05);A组总有效率与B组比较差异无统计学意义(P>0.05)。结论:沙丁胺醇联合丙酸倍氯米松治疗成人哮喘疗效优于两者单纯用药,值得推荐应用。

Objective： To investigate the effect of salbutamol combined with beclomethasone in treating adult with suffocative catarrh.Method： 84 cases with suffocative catarrh in our hospital from Jan.in 2008 to Jan.in 2009 were divided into the group A,group B and group C,group A received the treatment of salbutamol,group B received the treatment of beclomethasone,and group C received the treatment of salbutamol combined with beclomethasone.Result： The PEF of three groups after treatment was superior to that before treatment,and there was significant difference in them respectively（P0.05）.The PEF in the group A and in group B was superior to that in group C,and there was significant difference in them respectively（P0.05）.There was no significant difference on PEF in group A and group B（P0.05）.The days of symptomless in group A and in group B were fewer than those in group C,and there were significant difference in them respectively（P0.05）.There was no significant difference on days of symptomless in group A and group B（P0.05）.The total effective rate was 71.42% in B group,75.00% in group A and100.00% in group C,and the total effective rate in group A and in group B was lower than that in group C,and there was significant difference in them respectively（P0.05）.The total effective rate in group B was same to that in group A,and there was no significant difference in them respectively（P0.05）.Conclusion： The effect of salbutamol combined with beclomethasone in treating adult with suffocative catarrh is obvious,so they are worth being used widly.