田黄冲剂结合西医常规疗法治疗脑出血急性期临床对照研究

Clinical controlled study on "Tianhuang Granule" and western routine therapy for acute cerebral hemorrhage

目的观察田黄冲剂对脑出血急性期脑血肿、脑水肿及神经功能的影响。方法将60例急性脑出血患者随机分为治疗组和对照组各30例,两组均予西医常规治疗,治疗组同时加用田黄冲剂。两组疗程均为28天,观察治疗前和治疗期间各时段脑血肿体积、脑水肿体积及神经功能缺损评分(NIHSS)变化情况。结果两组脑水肿、脑血肿、NIHSS治疗后均明显改善(P<0.05)。组间脑血肿体积、脑水肿体积、NIHSS治疗前及治疗后第3天比较,差异无统计学意义(P>0.05);治疗后第7天、14天差异有统计学意义(P<0.05)。结论田黄冲剂对急性脑出血早期预防血肿及水肿扩大有明显的疗效,可明显改善患者的神经功能。

Objective To evaluate the effects of ＂Tianhuang Granule＂ on brain hematoma, cerebral edema and neurological function in patients with acute cerebral hem- orrhage. Methods Sixty subjects were randomly divided into two groups ： control group in which 30 eases were given conventional treatments and treatment group in which 30 eases were given conventional treatment and ＂Tianhuang Granule＂, with a course of 28 days. The volumes of brain hematoma and edema, and neurologic deficits score were measured before and after treatment. Results The volumes of brain hematoma and edema and NIHSS score were obviously improved in both groups（P 〈0.05 ）. They were of no difference between the two groups（ P 〉0.05 ） before treatment and on the third day; but they were significantly different between the two groups on the seventh and fourteenth days （P 〈0.05）. Conclusion ＂Tianhuang Granule＂ can obviously decrease the volumes of brain hematoma and edema, and improve the neurologic functions.