1Asano K,Shikama Y,Sbibuya Y,et al.Suppressive activity of tiotropium bromide on matrix metalloproteinase production from lung fibroblasts in vitro.Int J Chron Obstruct Pullnon Dis,2008,3:781-789.
3Bramhell SR,Neoptolemos JP,Stamp GW,et al.Imbelance of expression of matrix metalloproteinases(MMPs)and tissue inhibitors of the matrix metelloproteinases(TIMPs)in human pancreatic carcinoma.J Pathol,1997,182:347-355.
4Poulsom R,Pignateli M,Stetler-Stevenson WG,et al.Stromal expression of72Kda type Ⅳ collagenase(MMP-2)and TIMP2mRNAS in colorectal neoplasis.Am J Pathol,1992,141:389-396.
