经会阴前列腺癌冷冻治疗的并发症及其防治

Complications of Cryosurgical Ablation and Their Prevention and Treatment for Prostate Cancer

目的:探讨超声引导下经会阴前列腺癌靶向冷冻治疗的并发症及其防治。方法:对58例前列腺癌患者行超声引导下经会阴冷冻治疗,通过临床观察,分析其治疗后的并发症及原因,并总结防治措施。结果:尿失禁3～7天后恢复控尿16例(27.6%);永久尿失禁2例(3.4%);原有性交能力者18例中,术后出现勃起功能障碍1 2例(66.7%);产生尿道腐肉3例(5.2%);尿道直肠瘘、尿潴留、会阴部不适以及阴囊水肿各1例(1.7%)。结论:超声引导下经会阴前列腺癌靶向冷冻治疗的并发症发生率较低,且多数是可以预防和治疗的。

Objective：To investigate the complications of transrectal ultrasound guided percutaneous cryosurgical ablation for prostate cancer （CSAP） and their prevention and treatment. Methods：The data of 58 patients who were diagnosed with prostate cancer were summarized. The causes of the complications occurring after the （;SAP treatment, and their prevention and treatment were evaluated. Results.. 16 cases（27.6% ）had temporary incontinence for 3 -7 d; 2 cases（3.4 %） developed perpetual incontinence. Before operation 18 cases were potent, and among them 12 cases （66.7% ）had erectile dysfunction after operation. 3 cases developed urethral sloughing（5.2%）. Other complications were urethrorectal fistula （ 1.7 % ）, urinary retention （ 1.7% ）, perineal pain （ 1.7 % ） and scrotal oedema （ 1.7 % ）. Conclusions： The rate of complications of transrectal ultrasound-guided pereutaneous cryosurgical ablation for clinically prostate cancer is low and most complications can be prevented and cured.