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CD45^-和CD45^+成人急性淋巴细胞白血病患者的免疫表型及临床特点分析 被引量:2

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摘要 CD45是白细胞共同抗原(LCA),由一组高分子质量蛋白组成,除红细胞、血小板和浆细胞外,这些蛋白可选择性地表达在所有造血细胞表面。有研究提示CD45参与造血细胞生长、分化及B淋巴细胞的活化和凋亡,而且有报道提示原始细胞缺乏CIM5的急性淋巴细胞白血病(ALL)预后较好。我们应用四色流式细胞术CD45/SSC设门法分析48例ALL患者的免疫表型及细胞周期,以期了解ALL患者CD45表达与其他免疫表型、临床特征及预后的相关性。
出处 《中华血液学杂志》 CAS CSCD 北大核心 2010年第3期198-200,共3页 Chinese Journal of Hematology
基金 “十一五”国家科技支撑计划项目(2008BA161B02) 天津市科技支撑计划项目,重大疾病防治专项基金(07ZCGYSF00600)
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  • 1刘艳荣,王卉,常艳,程翼飞,付家瑜,张乐萍,刘桂兰,陈珊珊.四色流式细胞术检测急性B淋巴细胞白血病残留细胞[J].中华血液学杂志,2005,26(6):327-331. 被引量:13
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