健康人1562名臂踝脉搏波速度及其影响因素初探

Brachial-ankle pulse wave velocity and its risk factors in 1562 healthy people

目的探讨健康人臂踝脉搏波速度(baPWV)及其影响因素的相关性。方法应用动脉硬化检测仪VP-1000(BP203RPE,Ⅱ型,PWV/ABI型)测量1562名健康人臂踝脉搏波速度,并检测空腹血糖、血脂等血清生化指标。结果多元逐步回归分析显示,年龄(β=0.367,P<0.01)、收缩压(β=0.576,P<0.01)、空腹血糖(β=0.08,P<0.01)、男性(β=0.072,P<0.01)、体质量指数(BMI)(β=-0.098,P<0.01)是影响baPWV的独立危险因素(累积R^2=0.671)。结论 baPWV与年龄、男性性别、收缩压、空腹血糖存在正相关,与BMI成负相关。

Objective To investigate the correlation of brachial-ankle pulse wave velocity （baPWV） and its risk factors in healthy people. Methods Arteriosclerosis Detector VP-1000 （ BP203RPE, type Ⅱ PWV/ABI） was used to measure baPWV, and serum biochemical parameters,including fasting-blood sugar and lipids were also detected in 1562 healthy people for medical examination. Results Multiple stepwise regression analysis demonstrated that age, systolic pressure, blood-fasting sugar, male and body mass index were the independent risk factors to baPWV （R2 = 0. 671, all P 〈 0. 01）, and the standardized regression coefficients were 0. 367, 0. 08, 0. 08, 0. 072 and -0. 098, respectively. Conclusions baPWV is positively correlated with age, male, systolic pressure and fasting-blood sugar, but negatively correlated with body mass index.