中药复方在鸡胚水平上抗鸡新城疫病毒的作用研究

Researching on the Effects of Chinese Herbal Compound Anti Newcastle Disease Virus on Chick Embryo Level

本试验以中药百花蛇舌草、金银花等清热解毒药为主药,辅以黄芪、甘草等补气药组成中药复方,以水萃取浓缩制备中药复方流浸膏。以鸡新城疫病毒(NDV)为模式病毒,在鸡胚水平上以鸡胚平均死亡时间(MDT)和鸡胚尿囊液血凝价作为检测指标。结果表明,中药复方流浸膏与NDV感作和不感作均对NDV有明显的抑制作用,延长鸡胚死亡时间,降低血凝价,为临床用药提供了试验依据。

Chinese medicine Herba Hedyotis diffusa Willd.and Microsphaera linicerae Wint.in Rabenh and other heat-clearing and detoxifying drug as basis,supplementing with Astragalus membranaceus（Fisch.） Bunge and Glycyrrhiza uralensis Fisch.,fluidextract is concentrated by water extraction.With Newcastle disease virus（NDV） as a model virus,the average time of death（MDT） and allantoic fluid HA on the chick embryo level were used as measurement indicators,the results indicate that Chinese herbal compound fluidextract significantly inhibited NDV no matter effected or not,extending MDT of the chicken embryo and reducing HA,which provides experimental basis for clinical medicine.