N-异丙基丙烯酰胺共聚物的合成及温敏性

Synthesis and Thermo-Sensitive Research of N-Isopropylacrylamide Copolymers

温度敏感性高分子聚(N-异丙基丙烯酰胺)(PNIPAAm)在水溶液中有较低临界溶解温度(LCST)。文中采用两种新型温度敏感性单体甲基四氢呋喃丙烯酰胺(THFAA)和甲基四氢呋喃甲基丙烯烯酰胺(THFMA),均聚合成了亲水性较好且其LCST高于PNIPAAm的两种聚合物。用THFAA,THFMA与PNIPAAm进行自由基共聚合,研究了共聚物的组成对共聚物较低临界溶解温度的影响。结果表明,两种温度敏感性单体共聚能有效地改变共聚物的LCST,通过改变聚合时两种单体的摩尔配比制备共聚物P(NIPAAm-co-THFAA)及P(NIPAAm-co-THFMA),可以实现LCST的可控调节。

Temperature sensitive polymer,poly（N-isopropyl acrylamide） （PNIPAAm） in aqueous solution has a lower critical solution temperature （LCST）. In this work,two new temperature-sensitive polymers,poly（tetrahydrofurfulylacrylamide） （PTHFAA） and poly（tetrahydrofurfulylmethacraylamide） （PTHFMA） was synthesized,which are more hydrophilic and have higher lower critical solution temperature than PNIPAAm. THFAA or THFMA were also copolymerized with N-isopropyl acrylamide by radical copolymerization,respectively. The effect of composition of the copolymer on the LCST was studied. The results show that,by changing the mole ratio of monomer in copolymerization,the LCST of the copolymers can be effectively designed. The copolymers,P（NIPAAm-co-THFAA） and P （NIPAAm-co-THFMA） with different monomer molar ratios can achieve the aim to control the LCST.