心肌肌钙蛋白T在急性心肌梗死诊断中的意义

The significance of T(cTnT) in the diagnosis of AMI

目的探讨心肌肌钙蛋白T(cTnT)在急性心肌梗死(AMI)诊断中的意义。方法同时测定患者血清中的cTnT,肌酸激酶同工酶(CK-MB),统计出住院被确诊为AMI患者在早期这两项指标的阳性率,然后比较其敏感性、特异性。结果在AMI患者就诊时cTnT的阳性率是89%而CK-MB的阳性率是45%,cTnT和CK-MB两组数据差异有统计学意义(P<0.01)。观察AMI患者cTnT阳性持续时间可达14d左右。结论在诊断AMI时,cTnT具有检测方便、快速,出现时间早,敏感性、特异性高,对AMI患者的早期诊断具有很好的价值。

Objective To inquire into the significance of T（cTnT）in the diagnosis of AMI. Methods First, the cTnT and CK-MB indexes in the pantients＇ serum are tested;then,the positive ratios of the two items of AMI patients are calculated statistically; finally, their sensitive and atopy properties are compared. Results When AMI patiens first came the see the doctor,the positive ratio of their cTnT were 89%, while their CK-MB positive ratio was 45% ,and a statistical difference exists between the two groups （P〈0.01）. The observation of the AMI patiens＇ cTnT positive ratio could last for about 14 days. Conclusion When diagnosing AMI,the cTnT test is of great value in the early diagnose of AMI, as it enjoys not only the advantages of being convenient, fast and sensitive, but also the advantages of high atopy. In addition, the outcome of the test item could appear earlier.