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阿托伐他汀与胺碘酮联合对阵发性房颤的窦性心律维持作用的临床观察 被引量:1

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摘要 目的 观察阿托伐他汀与胺碘酮联合对阵发性房颤的窦性心律维持作用。方法将符合入选条件的患者随机分为两组,对照组给予胺碘酮(商品名可这龙,赛诺菲圣德堡民生药业生产)200mg、每天3次口服、连续5d;然后200mg、每天2次口服、连续5d;其后200mg、每天1次口服长期应用。实验组阿托伐他汀(商品名立普妥,辉瑞制药有限公司生产)+胺碘酮,阿托伐他汀20mg/d,胺碘酮使用方案同对照组。结果治疗组房颤发生率为:11%,对照组房颤发生率为:28%。结论他汀类药物与胺碘酮合用可以有效地预防阵发性房颤的发生,更好的维持窭性心律,减少胺碘酮的用量,降低胺碘酮的副作用。且不增加副作用。
作者 杨清泉
出处 《医学信息》 2010年第5期1440-1441,共2页 Journal of Medical Information
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