肠内营养治疗对机械通气患者的影响

Clinical Research of Nutritional Support Treatment for COPD Complicated with Respiratory Failure

目的:研究慢性阻塞性肺疾病(COPD)患者机械通气时营养支持治疗对患者营养状况和免疫功能的影响。方法:30例COPD机械通气患者分为肠内营养治疗组(EN组)和肠外营养治疗组(PN组),治疗10d,观察治疗前后营养指标及血清免疫指标的变化。结果:两组患者治疗后血清白蛋白、前白蛋白、上臂肌围、肱三头肌皮褶厚度、TLC、CD4、CD4/CD8较治疗前升高(P<0.05),其中EN组较PN组明显升高,差异有统计学意义(P<0.05),而且EN组缩短机械通气时间,降低ICU住院时间,减少治疗费用。结论:肠内营养和肠外营养均能改善COPD机械通气患者的营养状况及免疫功能,肠内营养在临床疗效上优于肠外营养。

Objective：To investigate the effects of nutritional support on nutritional status and immune function,and used mechanical ventilation（MV）to treat COPD Patients.Methods：30 patients with mechanical ventilation were divided into enteral nutrition group（EN group）and parenteral nutrition group（PN group）.After 10 days treatment,Observed the change of nutritional status and immune function.Results：TSF,MAMC,ALB,PAB,TLC,CD4,CD4/CD8 were higher than that before treatment in two groups（P〈0.05）,and EN group was higher than PN group（P〈0.05）.EN group could shorten treatment time and reduced the cost of treatment.Conclusions：Enteral nutrition and parenteral nutrition are effective therapy of COPD,the clinical efficacy of enteral nutrition is superior to parenteral nutrition.