脊髓损伤病人血脂变化相关因素分析

Analysis of lipid profiles in patients with spinal cord injury

目的:探讨脊髓损伤病人血脂谱的变化与性别、年龄、损伤特征、肢体功能训练次数的相关性。方法:选择脊髓损伤一年以上的住院病人,空腹测定血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白-胆固醇(LDL-C)、高密度脂蛋白-胆固醇(HDL-C)含量,应用单变量线性回归分析这四种脂蛋白与性别、年龄、损伤特征、肢体功能训练次数的关系。结果:HDL-C含量与每周肢体功能训练次数显著相关(β=0.034,P<0.005),LDL-C(β=0.031,P<0.038)、TC(β=0.54,P<0.003)与年龄显著相关。TG与年龄无显著相关,脂蛋白谱与损伤水平、完全/不完全损伤、性别无显著相关。结论:脊髓损伤病人的高密度脂蛋白-胆固醇含量与功能训练次数显著相关,运动训练有利于改善患者的脂蛋白谱。

Objective： To analyze the relations among lipid profiles and sex, age, characteristics of injury and times of exercise training in patients with spinal cord injury. Methods： The relations among levels of total cholesterol （TC）, triglyceride （TG）, low-density lipoprotein cholesterol C （LDL-C）, high-density lipoprotein-cholesterol C （HDL-C）, and sex, age, characteristics of injury and exercise training were analyzed by linear regression in 35 patients with spi- nal cord injury. Results： HDL-C was significantly correlated with times of training （β = 0. 034, P〈0. 005）. The LDL-C （β=0. 031, P〈0. 038） and TC （β=0.54, P〈0. 003） were significantly related with age. The Lipid profiles were not related with injury level, complete/incomPlete injury. Conclusion： Exercise training can improve lipid profiles, increase HDL-C level in patients with spinal cord injury.