摘要
水蛭素是医用水蛭的唾液腺分泌的一种多肽,由65～66个氨基酸组成,是目前活性最强的特异性凝血酶抑制剂。本文重点综述了目前国内外关于重组水蛭素分离纯化和检测这两方面的研究与应用方法,分析了这些方法的优缺点,并对重组水蛭素的前景作了展望。
Hirudin is a polypeptide of the medical leech salivary gland secretion, 65 to 66 amino acids, is the most active specific thrombin inhibitor. This article focuses on an overview of current domestic and foreign recombinant hirudin on the purification and detection of both research and application of method to analyze the advantages and disadvantages of these methods, and recombinant hirudin prospects are described.
出处
《食品与发酵科技》
CAS
2010年第2期10-15,共6页
Food and Fermentation Science & Technology
关键词
重组水蛭素
表达
纯化
检测方法
展望
hirudin
expression
purification
detection methods
prospect
