摘要
目的观察西酞普兰治疗脑梗死后强哭发作的治疗效果。方法脑梗死后强哭发作患者52例，按入院先后顺序随机分为2组，西酞普兰组27例，对照组25例。对照组给予常规脑血管病治疗，西酞普兰治疗组在此基础上加用西酞普兰20mg，1次／a，连服3个月，比较2组治疗后总有效率和长谷川痴呆量表积分。结果西酞普兰组和对照组总有效率分别是88．9％（25／27）和36．0％（9／25）；长谷川痴呆量表积分是（8．43±2．21）分和（6．24±2．02）分，两者差异均有统计学意义（P〈0．01）。结论西酞普兰治疗强哭发作效果好，不但能控制强哭发作，而且能提高患者的认知功能。
Objective To investigate the efficacy of citalopram on treatment of pathological crying after cerebral infarction. Methods Fifty-two patients with pathological crying symptoms after cerebral infarction were randomly divided into two groups ： citalopram treatment group （27 cases） and control group （25 cases）. Control group had conventional cerebmvascular disease treatment. Citalopram treatment group was treated with citalopram 20 mg/＇day for 3 months. The response rates and Hasegawa Dementia Scale （HDS） between two groups at the end of treatment were compared. Results There were significant differences in the response rates （88.9% and 36% ,respectively） and HDS（8.43 ±2.21 and 6.24 ±2. 02, respectively） between citalopram group and control group after treatment （P 〈 0.01 ）. Conclusions The study shows that citalopram is effective for treating pathological crying after cerebral infarction. Citalopram can not only control pathological crying, but also improve cognitive function in patients with cerebral infarction.
出处
《中国医药》
2010年第5期401-402,共2页
China Medicine
关键词
脑梗死
强哭
治疗
西酞普兰
Cerebral infarction
Pathological crying
Treatment
Citalopram
