期刊文献+

组织细胞坏死性淋巴结炎的临床与病理 被引量:3

下载PDF
导出
摘要 目的探讨组织细胞坏死性淋巴结炎的临床和病理学特点。方法回顾性分析38例组织细胞坏死性淋巴结炎的临床资料。结果本组主要表现为持续发热(84.2%)、单发(60.5%)或多发(39.5%)淋巴结肿大、多形性皮疹(21.1%)、外周血白细胞降低(65.8%)、红细胞沉降率增快(50.0%),丙氨酸转氨酶升高(31.6%),仅6例伴流感样上呼吸道症状(15.8%)。淋巴结活检特点为不同程度的凝固性坏死伴多种形态的组织细胞、淋巴细胞浸润,无中性粒细胞浸润。免疫组织化学染色示组织细胞CD68及T细胞CD3、CD45RO阳性,CD15、CD20及CD30均阴性。抗生素治疗无效,小剂量糖皮质激素治疗有效,所有病例经治疗后无复发。结论组织细胞坏死性淋巴结炎的临床表现无特异性,易误诊,确诊主要依靠活检及免疫组织化学检查,抗生素治疗无效,糖皮质激素治疗有效,预后良好。
出处 《临床误诊误治》 2010年第4期353-354,共2页 Clinical Misdiagnosis & Mistherapy
  • 相关文献

参考文献7

  • 1Bosch X,Guilabert A,Miquel R,et al.Enigmatic Kikuchi-Fujimoto disease:a comprehensive review[J].Am J Clin Pathol,2004,122(1):141-152.
  • 2Kuo T T.Kikuchi's disease (histiocytic necrotizing lymphadenitis).A clinicopathologic study of 79 cases with an analysis of histologic subtypes,immunohistology,and DNA ploidy[J].Am J Surg Pathol,1995,19(7):798-809.
  • 3张宝玉.成人Burkitt淋巴瘤一例误诊[J].临床误诊误治,2009,22(10):99-99. 被引量:4
  • 4Rosai J,原著,回允中,主译.外科病理学[M].9版北京:北京大学医学出版社,2006:1894.
  • 5Koybasi S,Saydam L,Gungen Y.Histiocytic necrotizing lymphadenitis of the neck[J].Am J Otolaryngol,2003,24(5):344-347.
  • 6Taguri A H,McIlwaine G G.Bilateral panuveitis:a possible association with Kikuchi-Fujimoto disease[J].Am J Ophthalmol,2001,132(3):419-421.
  • 7Ura H,Yamada N,Torii H,et al.Histiocytic necrotizing lymphadenitis (Kikuchi's disease):the necrotic appearance of the lymph node cells is caused by apoptosis[J].J Dermatol,1999,26(3):385-389.

共引文献3

同被引文献39

  • 1许志斌,高雪梅,陈训安.组织细胞坏死性淋巴结炎一例误诊误治[J].临床误诊误治,2011,24(S1):73-73. 被引量:1
  • 2回允中.外科病理学[M].第9版.北京:北京大学医学出版社,2006:1905.
  • 3Han HJ,Lim GY,Yeo DM,et al.Kikuchi's disease in children:clinical manifestations and Imaging features[J].J Korean Med Sci,2009,24(6):1105-1109.
  • 4Xavier B,Antonio G,Rosa M,et al.Enigmatic Kikuchi-Fujimoto Disease:a comprehensive review[J].AM J Clin Pathol,2004,122(1):141-152.
  • 5Charalabopoulos K,Papalimneou V,Charalabopoulos A,et a1.Brueella melitensis infection stimulates an immune response leading to Kikuchi-Fujimoto disease[J].In Vivo,2003,17(1):51-53.
  • 6Vassallo J,Coelho Filho JC,Amaral VG.Histioeytie necrotizing lymphadenitis (KikuChi lymphadenitis)in an HIV-positive patient[J].Rev lnst Med Trop Sao Paulo,2002,44(5):265-268.
  • 7Stephan JL,Jeannoel P,Chanoz J,et a1.Epstein-Barr virus-associated Kikuchi disease in two children[J].J Pediatr Hematol Oncol,200l,23(4):240-243.
  • 8Chien-Yu Cheng,Wang-Huei Sheng,Yi-Chun Lo,et al.Recurrent Kikuchi's Desease and autoimmune diseases[J].J Microbiol Immunol Infect,2010,43(5):366-371.
  • 9Tanaka T,Ohmori M,Yasunaga S,et al.DNA typing of HLA class II genes (HLA-DR,-DQ and -DP) in Japanese patients with histiocytic necrotizing lymphadenitis(Kikuchi's disease)[J].Tissue Antigens,1999,54(3):246-253.
  • 10Nomura Y,Sugita Y,Yoshida S,et al.Estimation of apoptosis and cell proliferation in histiocytic necrotizing lymphadenitis using immunohidtochemical double staining[J].Pathol Int,2008,58(2):98-103.

引证文献3

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部